2025 Lexus Es 350 Hybrid Mpg. Available with gasoline and hybrid powertrains, the es offers plenty of space and comfort for families that don’t want to ride in an suv. See our expert review on the 2025 lexus es hybrid and where it ranks among other luxury midsize cars.

The 2025 lexus es hybrid costs $44,590 The 2025 lexus es has great fuel economy figures for the midsize segment.